skin physiology Archives - KindofStephen https://www.kindofstephen.com Hello! I'm a skincare and cosmetic formulator. Here's my thoughts on skin care and cosmetic research. Fri, 11 May 2018 00:19:23 +0000 en-CA hourly 1 https://wordpress.org/?v=5.9.3 https://i0.wp.com/www.kindofstephen.com/wp-content/uploads/2017/06/cropped-profile-2.jpg?fit=32%2C32&ssl=1 skin physiology Archives - KindofStephen https://www.kindofstephen.com 32 32 114122149 New Mechanism That Regulates the Formation of Skin Discovered https://www.kindofstephen.com/new-mechanism-that-regulates-the-formation-of-skin/ Sun, 01 Feb 2015 13:03:57 +0000 http://kindofstephen.nfshost.com/2015/02/01/new-mechanism-that-regulates-the-formation-of-skin/ New Mechanism That Regulates the Formation of Skin Discovered The published work shows that Fra-2, a transcription factor, plays a key regulatory role in epidermis formation. “With the help of specific mouse models we demonstrate that the expression of Fra-2 in keratinocytes induces the expression of genes in the Epidermal Differentiation Complex (EDC)” the authors […]

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]]> New Mechanism That Regulates the Formation of Skin Discovered

The published work shows that Fra-2, a transcription factor, plays a key regulatory role in epidermis formation.

“With the help of specific mouse models we demonstrate that the expression of Fra-2 in keratinocytes induces the expression of genes in the Epidermal Differentiation Complex (EDC)” the authors write.

Conversely, loss of Fra-2 in suprabasal keratinocytes was sufficient to cause skin barrier defects, due to reduced expression of EDC genes

"New Mechanism That Regulates the Formation of Skin Discovered" on KindofStephen.

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